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Drug & Alcohol Rehab Centers in Knoxville, Tennessee

Discover 16 addiction treatment facilities in Knoxville. Our comprehensive directory helps you find the right rehabilitation center with 24/7 support available, licensed facilities, and insurance accepted at most locations. Whether you need detox services, residential treatment, outpatient programs, or sober living arrangements, find the perfect match for your recovery journey.

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Showing 16 of 16 results

Cedar Recovery
+9 photos
Cedar Recovery

South Knoxville

2805 West Governor John Sevier Highway, 37920
865-298-3558
Cedar Recovery in Knoxville, TN provides comprehensive substance use treatment through both outpatient and residential settings. Specializing in evidence-based approaches including cognitive behavioral therapy, trauma counseling, and medication-assisted treatment with methadone and buprenorphine, the facility serves individuals across all stages of recovery. As a SAMHSA-certified opioid treatment program and Federally Qualified Health Center, Cedar Recovery combines clinical expertise with accessible, flexible care options including telemedicine services.
Substance use treatment
Cedar Recovery
+9 photos
Cedar Recovery

East Knoxville

8712 Asheville Highway, 37924
865-932-3633
Cedar Recovery is a CARF-accredited substance use treatment center in Knoxville, TN, specializing in evidence-based outpatient care with medication-assisted treatment options including methadone and buprenorphine. The facility combines behavioral therapies like cognitive behavioral therapy, motivational interviewing, and trauma-informed counseling with flexible telemedicine services for accessible recovery support. Cedar Recovery's comprehensive approach addresses co-occurring anger management and relapse prevention, making it a trusted resource for individuals seeking personalized addiction treatment in East Tennessee.
Substance use treatment
Cherokee Health Systems
+9 photos
2018 Western Avenue, 37921
865-544-0406
Cherokee Health Systems in Knoxville, TN is a Federally Qualified Health Center specializing in integrated treatment for substance use disorders and co-occurring mental health conditions. The facility offers evidence-based approaches including cognitive behavioral therapy, motivational interviewing, and trauma-informed care across multiple outpatient settings. Their comprehensive programming addresses the complex needs of adults and children struggling with addiction and serious mental illness simultaneously.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Crossroads Treatment Centers
+9 photos
7039 Maynardville Pike, 37918
800-805-6989
Crossroads Treatment Centers in Knoxville, TN specializes in comprehensive substance use disorder treatment with a particular focus on supporting pregnant and postpartum women. The facility offers outpatient programs including medication-assisted treatment with methadone, buprenorphine, and naltrexone, combined with evidence-based counseling and telemedicine options for flexible access to care. Their relapse prevention strategies and specialized maternal support services make them a compassionate resource for women navigating recovery during critical life stages.
Substance use treatment
Knox Area Rescue Ministries
+9 photos
Knox Area Rescue Ministries

Serenity Ministries

- - -, 37917
865-673-6551
Knox Area Rescue Ministries in Knoxville, TN provides specialized long-term residential substance use treatment for adult women, combining evidence-based counseling with structured transitional housing. The facility integrates 12-step principles, trauma-informed care, and relapse prevention strategies to support lasting recovery. Their comprehensive approach addresses anger management and motivational barriers while offering flexible telemedicine options for continued therapeutic support.
Substance use treatmentTransitional housing, halfway house, or sober home
A DUI and Defensive Driving School Inc
+7 photos
111 Center Park Drive, 37922
865-335-5286
A DUI and Defensive Driving School Inc in Knoxville, TN specializes in substance use treatment with a focus on cognitive behavioral therapy for individuals involved with the criminal justice system. Serving adolescents, young adults, and women, this outpatient facility combines evidence-based addiction treatment with educational programming. Accredited by multiple state agencies and the Council on Accreditation, they provide compassionate, structured care for those seeking recovery from substance use disorders.
Substance use treatment
Cumberland Heights
+5 photos
Cumberland Heights

Outpt Serv of Knoxville/Papermill

1320 Papermill Pointe Way, 37909
865-213-9003
Cumberland Heights in Knoxville, TN is a state-accredited substance use treatment provider offering both intensive outpatient and standard outpatient programs. The facility specializes in evidence-based therapies including cognitive behavioral therapy, motivational interviewing, and trauma-informed care, with additional support through telemedicine options for accessibility. Their comprehensive approach combines 12-step facilitation with modern clinical interventions like contingency management and relapse prevention to address the complex needs of individuals in recovery.
Substance use treatment
Health Connect America
+5 photos
5743 Western Avenue, 37921
865-247-7045
Health Connect America in Knoxville, TN specializes in integrated substance use and mental health treatment for both adults and adolescents. The facility offers evidence-based approaches including cognitive behavioral therapy, motivational interviewing, and trauma-focused counseling, with flexible delivery through both in-person intensive outpatient and telehealth options. Accredited by the Council on Accreditation and state agencies, they serve individuals with co-occurring disorders and those involved in the criminal justice system.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Helen Ross McNabb Center
+5 photos
201 West Springdale Avenue, 37917
865-637-9711
Helen Ross McNabb Center in Knoxville, Tennessee provides comprehensive substance use treatment and dual diagnosis care for adults and seniors dealing with co-occurring mental health and addiction disorders. The center delivers evidence-based therapies including cognitive behavioral therapy, motivational interviewing, and trauma-focused counseling across multiple treatment settings—from intensive outpatient programs to medication-assisted treatment with methadone and buprenorphine. Accredited by CARF and state agencies, the center specializes in helping clients rebuild recovery through personalized, clinically rigorous care.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Helen Ross McNabb Center
+5 photos
Helen Ross McNabb Center

Knox County Adult Center

205 West Springdale Avenue, 37917
865-637-9711
Helen Ross McNabb Center in Knoxville, TN specializes in integrated substance use and mental health treatment for adults and children facing co-occurring disorders. Their evidence-based approach combines motivational interviewing, trauma-focused counseling, and relapse prevention within flexible intensive outpatient and outpatient settings. Accredited by CARF and state agencies, they serve diverse populations including those with HIV/AIDS and histories of sexual abuse.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Cherokee Health Systems
+3 photos
2202 Martin Luther King Jr Avenue, 37915
865-522-6097
Cherokee Health Systems in Knoxville, TN is a federally qualified health center specializing in substance use treatment and co-occurring mental health disorders for both adults and children. They offer comprehensive outpatient services including medication-assisted treatment with methadone, buprenorphine, and naltrexone, combined with evidence-based therapies like cognitive behavioral therapy and trauma counseling. Their integrated approach addresses the root causes of addiction while managing serious mental illness or emotional disturbance simultaneously.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
BHG Knoxville Citico Treatment Center
+2 photos
412 Citico Street, 37921
865-522-0661
BHG Knoxville Citico Treatment Center in Knoxville, TN specializes in comprehensive substance use disorder treatment with a focus on evidence-based detoxification and medication-assisted therapy. The facility offers flexible outpatient programming including intensive treatment, regular counseling, and on-site methadone and buprenorphine services. Accredited by The Joint Commission and SAMHSA, this center provides personalized care from intake through relapse prevention.
DetoxificationSubstance use treatment
BHG Knoxville Bernard Treatment Center
+1 photos
626 Bernard Avenue, 37921
865-522-0161
BHG Knoxville Bernard Treatment Center in Knoxville, Tennessee specializes in comprehensive substance use disorder treatment with outpatient detoxification and medication-assisted options including methadone and buprenorphine. The facility combines evidence-based therapies—cognitive behavioral therapy, motivational interviewing, and trauma-informed counseling—with practical skills like relapse prevention and anger management. Recognized by The Joint Commission and SAMHSA-certified as an opioid treatment program, this center delivers flexible telemedicine options alongside in-person care.
DetoxificationSubstance use treatment
Helen Ross McNabb Center
+1 photos
5310 Ball Camp Pike, 37921
865-523-4704 x0
Helen Ross McNabb Center in Knoxville, Tennessee provides comprehensive detoxification and substance use treatment with specialized care for individuals managing co-occurring mental health conditions. The facility offers residential and short-term programs utilizing evidence-based approaches including cognitive behavioral therapy, motivational interviewing, and trauma-focused counseling. Accredited by CARF and state agencies, McNabb Center addresses complex addiction cases with compassionate, integrated care.
DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Cherokee Health Systems - Placeholder
538 West 5th Avenue, 37917
865-525-2104
Cherokee Health Systems in Knoxville, TN is a Federally Qualified Health Center specializing in comprehensive substance use disorder treatment, including specialized care for clients managing co-occurring pain and addiction. The facility offers evidence-based approaches such as cognitive behavioral therapy, motivational interviewing, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. Recognized by state mental health and substance use agencies, Cherokee Health Systems integrates trauma-informed care and telehealth options to meet diverse patient needs.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
EM Jellinek Center - Placeholder
130 Hinton Avenue, 37917
865-525-4627
EM Jellinek Center in Knoxville, TN provides comprehensive substance use treatment with integrated residential care, addressing complex needs including co-occurring mental health and pain disorders. The center offers evidence-based therapies including cognitive behavioral therapy, motivational interviewing, and 12-step facilitation across short-term and long-term residential settings. With specialized programming for veterans, military families, seniors, and individuals involved in the criminal justice system, EM Jellinek delivers personalized recovery pathways for diverse populations.
Substance use treatmentTransitional housing, halfway house, or sober home

Addiction Treatment in Knoxville

Knoxville is home to a diverse range of addiction treatment facilities, offering comprehensive care for individuals struggling with substance abuse and co-occurring mental health disorders. Whether you're a resident of Knoxville or traveling for treatment, you'll find quality rehabilitation centers that can help you begin your recovery journey.

Why Choose Treatment in Knoxville?

  • Accessibility: Multiple treatment centers throughout the city with various specializations
  • Quality Care: Licensed and accredited facilities with experienced professionals
  • Diverse Options: From luxury rehabs to affordable state-funded programs
  • Support Network: Strong recovery community with numerous support groups
  • Continuum of Care: Full spectrum from detox to aftercare services

Types of Programs Available

Treatment centers in Knoxville offer various levels of care to meet different needs:

  • Medical Detox: Safe, supervised withdrawal management
  • Inpatient/Residential: 24/7 care in a structured environment
  • Partial Hospitalization (PHP): Intensive day treatment programs
  • Intensive Outpatient (IOP): Flexible scheduling for working professionals
  • Standard Outpatient: Weekly therapy and support groups
  • Sober Living: Transitional housing for ongoing recovery support

Getting Started with Treatment

Finding the right treatment center in Knoxville starts with understanding your specific needs. Consider factors such as the type of substance use, any co-occurring mental health conditions, insurance coverage, and personal preferences for treatment approach. Many facilities offer free consultations to help you determine the right fit for your recovery journey.